Explore Removery's Clinical Advisory Board, Clinical Research, Abstracts and Safety Data

The Removery Clinical Advisory Board (CAB) is composed of suitably experienced clinicians from across the disciplines of medicine and allied health. The CAB has drawn on the experience, skills, and knowledge of these members to help shape Removery's clinical philosophy, standards, and advancement in tattoo removal.

Developed by the CAB, Removery Method serves as a proprietary best practice standard of care that emphasizes safety and clinical efficacy across Fitzpatrick Skin Types I–VI, with the objective of optimizing the total number of laser treatments required.

Recently developed by the CAB and implemented in October 2025, Removery Method Color serves as a proprietary best practice standard of care that emphasizes safety and clinical efficacy across the removal of colored ink across Fitzpatrick Skin Types I–IV, with the objective of optimizing the total number of laser treatments required.

Cosmetic ink tattoos, including eyebrows, can be challenging to treat as their metal salt pigments often shift color during laser exposure, leading to client dissatisfaction. To address this, the CAB developed and piloted a safe and effective single-treatment, multi-pass protocol, completing twenty-nine treatments with no adverse events and high client satisfaction.

Since its implementation in 2024, the protocol has been used in 1,536 treatments, optimizing both treatment outcomes and the client experience, and eyebrows are now among the highest-satisfaction procedures performed.

Laser tattoo removal of recently applied tattoos (less than 14 days old) was evaluated in a pilot study of twenty-four subjects seeking urgent removal, using a hydrogel pad in combination with standard Removery Method best practices. Based on these findings, the CAB developed the Fresh Ink best practices and standard of care to optimize safe and effective treatment for clients seeking immediate removal, supported by pilot results demonstrating no adverse events and strong clinical tolerance.

Since implementation, 384 clients have been treated safely with no increase in adverse event reporting, and Naama® outcomes, including treatments performed 24 hours, 3 weeks, and 6 weeks after application, were published and presented at the 2025 ASLMS Conference by Dr. William Kwan, board-certified dermatologist, Removery Co-CMO, and CAB member.

Qualitative interviews with tattoo artists indicate that brightly colored and gray-scale tattoos commonly contain multiple pigment types, with white pigment frequently added to enhance brightness or modify tonal depth. In our internal in vivo and in vitro studies, we were unable to induce paradoxical darkening in tattoos containing white ink, although the phenomenon remains scientifically plausible and has been reported in association with pigments containing titanium dioxide or iron oxide.

Paradoxical darkening is believed to result from photo-induced chemical reduction or structural alterations of pigment particles during laser exposure, causing them to appear darker rather than lighter. While these reactions are well described, they are not consistently reproducible, suggesting that factors such as ink pigment formulation, particle size, and carrier components influence risk. We are continuing our clinical research to better characterize these mechanisms and to further advance our approach for safe, effective and optimal treatment approaches for clients with tattoos containing white ink.

Join Dr. William Kwan, board-certified dermatologist at Golden State Dermatology - Beverly Hills and Co-CMO of Removery, for an engaging session on modern tattoo removal. Dr. Kwan will share Removery's demographic data, clinical best practices, and a series of complex tattoo removal cases during Tattoo Removal 360.

Following full implementation in 2023, Removery adopted a standardized clinical escalation reporting system to enable systematic monitoring, documentation, and resolution of client clinical inquiries, as well as reported adverse events related to laser tattoo removal.